D:A:D Study

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De D:A:D-studie (Data Collection on Adverse events of Anti-HIV Drugs) is een prospectieve studie, bestaande uit meerdere cohorten, die zich richt op de mogelijke relatie tussen het gebruik van antiretrovirale middelen en cardiovasculaire ziekten, ernstige leveren nierproblematiek en niet-aids-gerelateerde maligniteiten. Prof. Jens Lundgren (Rigshospitalet & University of Copenhagen) coördineert de studie, prof. dr. Peter Reiss is de principal investigator vanuit SHM/ATHENA.

Publicaties door D:A:D in 2015

Development and validation of a risk score for chronic kidney disease in HIV infection using prospective cohort data from the D:A:D study
Mocroft A, Lundgren JD, Ross M, Law M, Reiss P, Kirk O, Smith C, Wentworth D, Neuhaus J, Fux CA, Moranne O, Morlat P, Johnson MA, Ryom L; D:A:D study group; Royal Free Hospital Clinic Cohort; INSIGHT study group; SMART study group; ESPRIT study group.
PLoS Med 2015 Mar 31;12(3):e1001809

Cancer risk and use of protease inhibitor or non-nucleoside reverse transcriptase inhibitor based combination antiretroviral therapy: the D:A:D study
Bruyand M, Ryom L, Shepherd L, Fatkenheuer G, Grulich A, Reiss P, de Wit S, D’Arminio Monforte A, Furrer H, Pradier C, Lundgren J, Sabin C; D:A:D study group.
J Acquir Immune Defic Syndr 2015 Apr 15;68(5):568-77

An updated prediction model of the global risk of cardiovascular disease in HIV-positive persons: The Data-collection on Adverse Effects of Anti-HIV Drugs (D:A:D) study
Friis-Møller N, Ryom L, Smith C, Weber R, Reiss P, Dabis F, De Wit S, Monforte AD, Kirk O, Fontas E, Sabin C, Phillips A, Lundgren J, Law M;D:A:D study group.
Eur J Prev Cardiol. 2015 Apr 16 [Epub ahead of print]

Short-term weight gain after antiretroviral therapy initiation and subsequent risk of cardiovascular disease and diabetes: the D:A:D study
Achhra AC, Mocroft A, Reiss P, Sabin C, Ryom L, de Wit S, Smith CJ, d'Arminio Monforte A, Phillips A, Weber R, Lundgren J, Law MG; D:A:D Study Group.
HIV Med. 2015 Jul 28 [Epub ahead of print]

Cumulative and current exposure to potentially nephrotoxic antiretrovirals and development of chronic kidney disease in HIV+ persons with a normal baseline eGFR : A prospective international cohort study
Mocroft A, Lundgren JD, Ross M, Fux CA, Reiss P, Moranne O, Morlat P, d'Arminio Montforte A, Kirk O, Ryom L for the Data Collection on Adverse events of Anti-HIV Drugs (D:A:D) Study.
Lancet HIV 2015 Nov 17 [Epub ahead of print]