COHERE

Logo_Cohere.pngCOHERE (Collaboration of Observational HIV Epidemiological Research in Europe)
The Collaboration of Observational HIV Epidemiological Research in Europe (COHERE) is a unique collaboration of 33 cohorts in Europe that aims to conduct epidemiological research on the prognosis and outcome of HIV-positive populations from across Europe, including children, pregnant mothers, and other adults.

COHERE was part of EuroCoord, the collaboration that encompassed all EU-funded cohort studies in the field of HIV and that ended in 2015. For the time being, scientific productivity continues based on the last available joint dataset.

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In 2017, publications from COHERE included:

Reference curves for CD4+ T cell count response to combination of antiretroviral treatment in HIV-1 infected naive patients
Bouteloup V, Sabin C, Mocroft A, Gras L, Pantazis N, Le Moing V, d'Arminio Monforte A, Mary-Krause M, Roca B, Miro JM, Battegay M, Brockmeyer N, Berenguer J, Morlat P, Obel N, De Wit S, Fätkenheuer G, Zangerle R, Ghosn J, Pérez-Hoyos S, Campbell M, Prins M, Chêne G, Meyer L, Dorrucci M, Torti C, Thiébaut R; Standard Reference Distribution of CD4 Response to HAART Project Team for the Collaboration of Observational HIV Epidemiological Research Europe (COHERE) in EuroCoord.
HIV Med 2017 Jan;18(1):33-44

Inequalities by educational level in response to combination antiretroviral treatment and survival in HIV-positive men and women in Europe
Socio-economic Inequalities and HIV Working Group for Collaboration of Observational HIV Epidemiological Research in Europe (COHERE) in EuroCoord.
AIDS. 2017 Jan 14;31(2):253-262. doi: 10.1097/QAD.0000000000001270

Timing of cART initiation in male and female migrants living with HIV in Western Europe: an observational cohort study (1997-2013)
Migrant Health Working Group for the Collaboration of Observational HIV Epidemiological Research in Europe (COHERE) in EuroCoord.
AIDS. 2017 Jan 21. doi: 10.1097/QAD.0000000000001411. [Epub ahead of print]

Higher rates of triple-class virological failure in perinatally HIV-infected teenagers compared with heterosexually infected young adults in Europe
Judd A, Lodwick R, Noguera-Julian A, Gibb DM, Butler K, Costagliola D, Sabin C, van Sighem A, Ledergerber B, Torti C, Mocroft A, Podzamczer D, Dorrucci M, De Wit S, Obel N, Dabis F, Cozzi-Lepri A, García F, Brockmeyer NH, Warszawski J, Gonzalez-Tome MI, Mussini C, Touloumi G, Zangerle R, Ghosn J, Castagna A, Fätkenheuer G, Stephan C, Meyer L, Campbell MA, Chene G, Phillips A; Pursuing Later Treatment Options II (PLATO II) Project Team for the Collaboration of Observational HIV Epidemiological Research Europe (COHERE) in EuroCoord.
HIV Med. 2017 Mar;18(3):171-180. doi: 10.1111/hiv.12411. [Epub 2016 Sep 14]

Impact of CD4 and CD8 dynamics and viral rebounds on loss of virological control in HIV controllers
Chereau F, Madec Y, Sabin C, Obel N, Ruiz-Mateos E, Chrysos G, Fidler S, Lehmann C, Zangerle R, Wittkop L, Reiss P, Hamouda O, Estrada Perez V, Leal M, Mocroft A, Garcia De Olalla P, Ammassari A, D'Arminio Monforte A, Mussini C, Segura F, Castagna A, Cavassini M, Grabar S, Morlat P, De Wit S, Lambotte O, Meyer L; HIV Controllers Project Working Group for the Collaboration of Observational HIV Epidemiological Research Europe (COHERE) in EuroCoord.
PLoS One. 2017 Apr 5;12(4):e0173893. doi: 10.1371/journal.pone.0173893. eCollection 2017

Is response to anti-hepatitis C virus treatment predictive of mortality in hepatitis C virus/HIV-positive patients?
Peters L, Cozzi-Lepri A; Hepatitis C Working Group for the Collaboration of Observational HIV Research Europe (COHERE) in EuroCoord.
AIDS. 2017 Mar 13;31(5):661-668. doi: 10.1097/QAD.0000000000001378.

Optimal timing of antiretroviral treatment initiation in HIV-positive children and adolescents: a multiregional analysis from Southern Africa, West Africa and Europe
Schomaker M, Leroy V, Wolfs T, Technau KG, Renner L, Judd A, Sawry S, Amorissani-Folquet M, Noguera-Julian A, Tanser F, Eboua F, Navarro ML, Chimbetete C, Amani-Bosse C, Warszawski J, Phiri S, N'Gbeche S, Cox V, Koueta F, Giddy J, Sygnaté-Sy H, Raben D, Chêne G, Davies MA; IeDEA West and Southern Africa regional collaborations and COHERE in EuroCoord
Int J Epidemiol. 2017 Apr 1;46(2):453-465. doi: 10.1093/ije/dyw097

Comparison of Kaposi sarcoma risk in HIV-positive adults across five continents: a multiregional multicohort study
Bohlius J; AIDS-defining Cancer Project Working Group for IeDEA and COHERE in EuroCoord.
Clin Infect Dis. 2017 May 20. doi: 10.1093/cid/cix480. [Epub ahead of print]

Cohort Profile: Collaboration of Observational HIV Epidemiological Research Europe (COHERE) in EuroCoord
Chêne G, Phillips A, Costagliola D, Sterne JA, Furrer H, Del Amo J, Mocroft A, d'Arminio Monforte A, Dabis F, Miro JM, Barger D, Termote M, Schwimmer C, Salbøl Brandt R, Friis-Moller N, Raben D, Haerry D, Egger M, Weller I, De Wit S.
Int J Epidemiol. 2017 Jun 1;46(3):797–797n. doi:10.1093/ije/dyw211

CD4 cell count response to first-line combination ART in HIV-2+ patients compared with HIV-1+ patients: a multinational, multicohort European study
Wittkop L, Arsandaux J, Trevino A, Schim van der Loeff M, Anderson J, van Sighem A, Böni J, Brun-Vezinet F, Soriano V, Boufassa F, Brockmeyer N, et al. on behalf of the COHERE in EuroCoord and ACHIeV2e Study Group
J Antimicrob Chemother. 2017. dkx210, https://doi.org/10.1093/jac/dkx210

Immunological and virological response to antiretroviral treatment in migrant and native men and women in Western Europe; is benefit equal for all?
Migrant Health Working Group for the Collaboration of Observational HIV Epidemiological Research in Europe (COHERE) in EuroCoord.
HIV Med. 2017 Jul 25. doi: 10.1111/hiv.12536. [Epub ahead of print]